The asymmetrical currents & voltages will affect the components needed (e.g. transistors have to handle peak offset current & heat), in some applications, e.g. value of 1K R may be 39K on 100V. Higher currents may need darlingtons or P & N ch MOSFETs.
The above circuit should provide adequate balance for testing most things that need a balanced supply.
D1 provides some cross over bias keeping the transistors in class B, 2 diodes in series may do better, but easy to get into class AB/A & get hot when this is not needed!